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Anabolics & Catabolism

Anabolic and catabolic state /IGF-1 factor and insulin

The many biochemical processes that make up the body's metabolism can be grouped into two general categories - anabolism and catabolism. Anabolism is the building up of complex molecules, while catabolism is their breakdown. To build molecules and sustain life, the body needs energy. It gets this energy from the breakdown of nutrients such as glucose and fatty acids. So, for molecular construction to occur, molecular destruction must go on at the same time to release the energy required to drive the biochemical reactions. When anabolism exceeds catabolism, net growth occurs when anabolismexcesses anabolism net loss occurs.

Anabolism includes the chemical reactions that cause different molecules to combine to from larger, more complex ones. The net result of anabolism is the creation of new cellular material, such as enzymes, proteins, cells, cell membranes, and tissues. Anabolism is necessary for growth, maintenance, and tissue repair.
Catabolism includes the chemical reactions that break down complex molecules into simpler ones for energy production, for recycling of their molecular components, or for their excretion. If energy is produced, it is stored as glycogen or fat. Recently, the trend in sports nutrition has been to focus on anti-catabolic training methods and nutrients. For example, when the muscles are strenuously trained and the muscle fibers are damaged, cortisol is released at a higher level, speeding up the breakdown of tissues. Nutrients such as L-Glutamine have been shown to reduce the effects of cortisol, resulting in reduced tissue breakdown. Antioxidants and a number of phytochemicals also have anti-catabolic effects, as does high protein and all around good nutrition. By reducing the rate of catabolism, anabolism is increased, resulting in faster recovering, a higher level of performance, and an increased growth rate.

2. Muscle Catabolism:
Catabolism occurs in every person regardless of lifestyle or training level. We can see this because unused muscles, such as those immobilized by casts or those in comatose patients, atrophy. Catabolism is governed by various hormonal systems as well as by mechanical stress. In other words, elevated general stress levels (such as those experienced by people who are overworked) as well as specific mechanical stress (such as that inflicted by resistance training) are catabolic. That's right, weight training is catabolic, not anabolic. That's why resistance training often leads to muscle soreness - the soreness is an indication of muscle damage.
There are many ways to prevent catabolism. Eating frequently keeps blood sugar levels high, which keeps the body from cannibalizing muscle tissue for energy. Various drugs (so-called anabolic steroids among others) interfere with the body's natural hormonally regulated catabolic processes.
Obviously, any reduction in catabolism, if the rate of anabolism remains constant, will result in an increase in the rate of muscle growth. The rapid muscle gains experienced by steroid users show this.

What is IGF-1?
IGF-1, sometimes called IGF1, is made by the liver, "triggered" by hgh, and responsible for much of what is attributed to human growth hormone. It is also a good way to find out what your gh levels really are, because it is "volatile" and difficult to test for.

IGF-1, The Bodybuilder's Dream
Muscle MD magazine describes IGF-1 as "Possibly the Most Potent Bodybuilding Drug Ever!" Author T.C. Luoma, says that IGF-1 is available at some Southern California gyms. There are no controlled studies supporting the bodybuilder's claims of gaining up to 20 lb. of muscle mass but the evidence is increasing. Some of these bodybuilders say they have experienced a 5% drop in body fat in a month, while at the same time experiencing significant increases in lean muscle mass and strength. These bodybuilders seem convinced that IGF-1 can offer the benefits they have been hoping for.
Dr. Paolo trombetta , an expert in performance-enhancing compounds, but there is a rationale for the belief that HGH taken with IGF-1 will work better. There is a feedback mechanism between the human growth hormone in the pituitary gland and the IGF-1 in the liver. The human growth hormone stimulates the release of IGF-1, but when the levels of IGF-1 rise to a certain point in the circulation, it signals the shutdown of HGH release. But there is a lag time, which means that HGH levels increase at night and IGF-1 levels increase during the day. Bodybuilders hope that taking HGH and IGF-1 together will have a double-fisted effect on protein synthesis.
Assuming that you eat right, train properly, and get enough sleep, there are only two factors limiting your growth; the amount of anabolic, tissue building, and catabolic, tissue destroying, hormones in your blood.
Training causes your muscles to process anabolic hormones. To promote the optimum level of growth, you must learn how long to train before resting and allowing your body to replace the anabolic hormones that have been used up. If you over train, all of the anabolic hormones will be used up and the catabolic hormones will start to dominate. If you under train, you will waste some of the natural anabolic hormones that your body produces.

In the course of learning how to maximize your body's natural supply of anabolic hormones, you will go through some ups and downs. The catch 22 is that even if you do everything right, you will eventually reach a plateau that you cannot break through. The level of growth at which the plateau is reached is predetermined by the amount of anabolic hormones that your body naturally produces. The only way to break through the plateau is to raise the level of anabolic hormones in your blood.

Anabolic steroids artificially raise the amount of anabolic hormones in the blood and permit further growth. Unfortunately, anabolic steroids are illegal and dangerous to use. Many people have tried countless ergogenic products. The vast majority of these products were totally worthless or provided minute benefits that could easily be obtained through a proper diet. Most products currently on the market are merely expensive forms of reconstituted food. They may work wonders for malnourished individuals who don't have access to supermarkets, but they are a waste of money for healthy individuals. I have only been able to find one legal product that produces significant increases in muscle size and strength. It is called Insulin-like Growth Factor-1 (IGF-1 is also known as somatomedin C)
IGF-1 increases the level of anabolic hormones in your blood. This leads to faster recovery times, increased strength, and increased energy. Most importantly, it provides your muscles with the extra fuel they need to blast through plateaus and move on to the next level of growth. Increasing the level of anabolic hormones in your blood enables you to break through your body's natural limitations. It is the key to serious growth and the only way to build a freaky, professional bodybuilder type physique.

Insulin is a Hormone Secreted by the Pancreas
Insulin (derived from Latin insula, "island") is a hormone secreted by cells inside the pancreas - called islets of Langerhans - which plays a vital role in the regulation of carbohydrate metabolism. As well as being the body's source of insulin, the pancreas also produces digestive enzymes and other hormones, and plays an active part in the metabolism of fat (triglycerides) and proteins.

Insulin Helps Regulate Blood Glucose
Insulin is secreted by the pancreas into the bloodstream in response to an increase in blood sugar, caused by the metabolism of carbohydrates into glucose after a meal. The circulating insulin is grabbed by insulin-receptors located on body cells. After grabbing the insulin, the cell activates other receptors designed to absorb glucose from the blood stream into the inside of the cell. In this way, the insulin facilitates the absorption of glucose by the cells, causing a reduction in blood-glucose levels